许美玉

食品免疫学、免疫学
1、 植物蛋白生物活性研究。
2、 植物多酚对有害物质毒性的拮抗作用。
3、 林蛙油、林蛙皮肤免疫与生理功能研究。

教授课程：
本科教学：食品免疫学、免疫学、食品卫生学、功能性食品、饮食与健康等。
研究生教学：食品质量与安全检测新技术、食品加工与安全研究进展等。

受教育经历：
2001/04-2005/03 日本岐阜大学生物资源科学博士
1982/09-1987/07 吉林医学院医学检验学士
研究与工作经历：
2005/06-至今北京林业大学亚洲365副教授
1999/12-2001/03 日本岐阜大学生物资源利用科学访问学者
1987/07-1999/12 吉林医学院附属医院检验科主管检验医师

（1）.2014.1-2016.12：北京市自然科学基金面上项目（批准号8142029）：北京市机动车尾气中硝基酚类物质干扰大鼠性腺功能的生殖内分泌学研究。
（2）2012.7-2013.7：科技创新基地培育与发展工程专项（Z121106002812037）；核桃油加工的质量控制及其蛋白质多肽利用。
（3）2011/01-2015/12：国家自然科学基金资助子项目（J1103516-2D26）：山杏仁蛋白抑制人结肠癌细胞生长作用研究。
（4）2011.1-2014.12：林业公益性行业科研专项（201004081）；山杏加工利用产业链技术体系研发。
（5）2007.1-2008.12：教育部留学人员回国启动基金项目（教外司留2007.1108）：牛乳alpha-乳白蛋白和beta-乳球蛋白对肠细胞增殖的影响。
（6）2007.1-2007.12：国家自然科学基金面上项目项目（30670261）：普氏野马生殖内分泌学研究：非损伤性激素测定方法的应用。
（7）2006.1-2010.12：国家科技支撑计划子课题（2006BAD04A06）：奶粉脱敏技术与配方技术研究。

1. Xi Liqin, Hu Ruiqi, Guo Ting, Wang Yuhan, Sheng Xia, Han Yingying, Yuan Zhengrong, WengQiang, Xu Meiyu*.Immunoreactivities of NF-κB, IL-1β and IL-1R in the skin of Chinese brown frog (Rana dybowskii).ActaHistochem. 2016 Dec 2. pii: S0065-1281(16)30192-1. doi: 10.1016/j.acthis.2016.11.008. [Epub ahead of print]
2. HuRuiqi, XiLiqin, CaoQing, YangRui, LiuYuning, ShengXia, HanYingying, YuanZhengrong, GuoYan, WengQiang, Xu Meiyu*.The expression of prostaglandin-E2 and its receptor in the oviduct of Chinese brown frog (Rana dybowskii). Prostaglandins Other Lipid Mediat.2016 Jul;124:9-15. doi: 10.1016/j.prostaglandins.2016.05.006.
3. Yang Lubing, Ma Sihui, Han Yu, Wang Yuhan, Guo Yan, WengQiang, Xu Meiyu*.Walnut Polyphenol Extract Attenuates Immunotoxicity Induced by 4-Pentylphenol and 3-methyl-4-nitrophenol in Murine Splenic Lymphocyte. Nutrients 2016, 8, 287; doi:10.3390/nu8050287
4. Yang Lubing, Ma Sihui, Wan Yifang,DuanShuqi, Ye Siyan,Sheng Xia, WengQiang, Taya Kazuyoshi, Xu Meiyu*.In vitro effect of 4-pentylphenol and 3-methyl-4-nitrophenol on murine splenic lymphocyte populations and cytokine/granzyme production.J Immunotoxicol. 2016 Mar 31:1-9.
5. Hu Ruiqi, Liu Yuning, Deng Yu, Ma Sihui, Sheng Xia, WengQiang, Xu Meiyu*. Immunoreactivities of IL-1β and IL-1R in oviduct of Chinese brown frog (Rana dybowskii) during pre-hibernation and the breeding period. ActaHistochemica. 2016 Mar;118(2):164-169.
6. Ma Sihui, Huang Di, ZhaiMengxin, Yang Lubing, Peng Seng, Chen C, Feng X, WengQiang, Zhang Bolin, Xu Meiyu*. Isolation of a novel bio-peptide from walnut residual protein inducing apoptosis and autophagy on cancer cells. BMC Complementary and Alternative Medicine. 2015 Nov 23;15:413. doi: 10.1186/s12906-015-0940-9.
7. Weng Ji, Liu Yuning, Xu Ying, Hu Ruiqi, Zhang Haolin, Sheng Xia, Watanabe Gen, Taya K, WengQiang, XuMeiyu*. Expression of P450arom and Estrogen Receptor Alpha in the Oviduct of Chinese Brown Frog (Rana dybowskii) during Prehibernation. International journal of Endocrinology. 2015:283085. doi: 10.1155/2015/283085. Epub 2015 Feb 23.
8. Huang Di, Yang Lubing, Wang Chenlu, Ma Sihui, Cui Li, Huang Shiyang, Sheng Xia, WengQiang, Xu Meiyu*. Immunostimulatory activity of protein hydrolysate from oviductusranae on macrophage in vitro. Evidence-based Complementary and Alternative Medicine. 2014:180234. doi: 10.1155/2014/180234. Epub 2014 Dec 22.
9. Zhang Mengyuan, Sheng Xia, Sun Rongbo, Li Qinglin, Zhang Haolin, Zhou Jiao, Xu Meiyu*, WengQiang, Watanabe Gen, Taya Kazuyoshi. Seasonal changes in immunoreactivity of inhibin/activin subunits in the epididymis of wild ground squirrels (Citellusdauricus Brandt). Journal of Reproduction and Development. 2013;59(3):302-307.
10. Sheng Xia, WengJiaju, Zhang Haolin, Li Xiaonan, Zhang Mengyuan, Xu Meiyu*, WengQiang, Watanabe Gen, Taya Kazuyoshi. Immunohistochemical localization of inhibin/activin subunits in the wild ground squirrel (CitellusdauricusBrandt) ovary. Journal of Reproduction and Development. 2012;58(5):531-536.
11. Zhang Haolin, Sheng Xia, Hu Xiao, Li Xiaonan, Xu Hui, Zhang Mengyuan, Li Ben, Xu Meiyu*, WengQiang, Zhang Zhixiang, Taya Kazuyoshi. Seasonal changes in spermatogenesis and immunolocalization of cytochrome P450 17alpha-hydroxylase/c17-20 lyase and cytochrome P450 aromatase in the wild male ground squirrel (Citellusdauricus Brandt).Journal of Reproduction and Development. 2010 Jun;56(3):297-302.
12. Xu Meiyu, SugiuraYoshimasa, Nagaoka Satoshi, Kanamaru Yoshihiro*.Involvement of SDS-stable higher M(r) forms of bovine normal milk alpha-lactalbumin in inducing intestinal IEC-6 cell death. Bioscience, Biotechnology, and Biochemistry. 2005 Jun;69(6):1189-1192.
13. Xu Meiyu, SugiuraYoshimasa, Nagaoka Satoshi, Kanamaru Yoshihiro*. IEC-6 intestinal cell death induced by bovine milk alpha-lactalbumin. Bioscience, Biotechnology, and Biochemistry. 2005 Jun;69(6):1082-1089.
14. Liu Yuning, Weng Ji, Huang Shiyang, Shen Yong, Sheng Xia, Han Yingying, Xu Meiyu, WengQiang*.Immunoreactivities of PPARγ2, leptin and leptin receptor in oviduct of Chinese brown frog during breeding period and pre-hibernation.European journal of histochemistry. 2014 Sep 9;58(3):2422. doi: 10.4081/ejh.2014.2422.
15. Li Xiaonan, Zhang Haolin, Sheng Xia, Li Ben, Zhou Jiao, Xu Meiyu, WengQiang*, Watanabe Gen, Taya Kazuyoshi. Immunoreactivities of androgen receptor, estrogen receptors, p450arom, p450c17 proteins in wild ground squirrels ovaries during the nonbreeding and breeding seasons. Journal of ovarian research. 2012 Sep 25;5(1):26. doi: 10.1186/1757-2215-5-26.
16. WengQiang*, Tsubota Toshio, Dai Mingdao, WengJiaju, Tian Yang, Xu Meiyu, Watanabe Gen, Taya Kazuyoshi.Immunolocalization of steroidogenic enzymes and their expression during the breeding season in the testes of wild raccoon dogs (Nyctereutesprocyonoides).Animal science journal. 2012 Jul;83(7):535-542.
17. WengJiaju, Li Ben, Sheng Xia, Zhang Haolin, Hu Xiao, Zhou Jiao, Xu Meiyu, WengQiang*, Watanabe Gen, Taya Kazuyoshi.Seasonal changes in immunoreactivity of vascular endothelial factor and its receptors VEGFR1 and VEGFR2 in the uterus of wild ground squirrels (Citellusdauricus Brandt). Journal of Reproduction and Development. 2012;58(5):537-543.
18. Zhang Mengyuan, Sheng Xia, Zhang Haolin, Wang Qian, Xu Meiyu, WengQiang*, Watanabe Gen, Taya Kazuyoshi.Seasonal changes in morphology and immunoreactivity of PDGF-A and its receptor PDGFR-α in the epididymis of wild ground squirrels (Citellusdauricus Brandt). Journal of Reproduction and Development. 2012;58(3):353-359.
19. Li Ben, Sheng Xia, Song Moshi, Zhang Haolin, WengJiaju, Zhang Mengyuan, Hu Xiao, Zhou Jiao, Xu Meiyu, WengQiang*, Watanabe Gen, Taya Kazuyoshi. Expression of nerve growth factor and its receptors TrkA and p75 in the uterus of wild female ground squirrel (Citellusdauricus Brandt). General and comparative endocrinology. 2012 Mar 1;176(1):62-9.
20. Lu Lu, Zhang Haolin, Lv Na, Ma Xiaoting, Tian Long, Hu Xu, Liu Shuqiang, Xu Meiyu, WengQiang*, Watanabe Gen, Taya Kazuyoshi.Immunolocalization of androgen receptor, aromatase cytochrome P450, estrogen receptor alpha and estrogen receptor beta proteins during the breeding season in scent glands of muskrats (Ondatrazibethicus).Zoological Science. 2011 Oct;28(10):727-732.
21. Shen Yong, Liu Yuning, Ma Jiajia, Ma Xiaoting, Tian Yang, Zhang Haolin, Li Lin, Xu Meiyu, WengQiang*, Watanabe Gen, Taya Kazuyoshi.Immunoreactivity of c-kit receptor protein during the prehibernation period in the oviduct of the Chinese brown frog, Rana chensinensis.Journal of Veterinary Medical Science. 2012 Feb;74(2):209-213.
22. Ma Xiaoting, Zhang Haolin, WengJiaju, Sheng Xia, Lu Lu, Hu Xiao, Liu Shuqiang, Xu Meiyu, WengQiang*, Watanabe Gen, Taya Kazuyoshi.Immunolocalization of inhibin/activin subunit proteins during the breeding season in testes and scented glands of muskrats (Ondatrazibethicus).Journal of Veterinary Medical Science. 2011 Sep;73(9):1199-1205.
23. Li Qinglin, Weng Ji, Zhang Haolin, Lu Lu, Ma Xiaoting, Wang Qike, Cao Han, Liu Shuqiang, Xu Meiyu, WengQiang*, Watanabe Gen, Taya Kazuyoshi.Immunohistochemical evidence: testicular and scented glandular androgen synthesis in muskrats (Ondatrazibethicus) during the breeding season.European journal of histochemistry. 2011 Oct 19;55(4):e32. doi: 10.4081/ejh.2011.e32.