何湘伟

1.微生物学研究的新技术和新方法

2.微生物天然产物资源的开发利用

3.微生物毒性评价

2002年9月-2006年7月北京大学，元培学院，获化学学士学位

2006年9月-2011年7月北京大学，化学分子与工程学院，获化学生物学博士学位

2011年7月-2013年6月清华大学，化学系，博士后

2013年6月至今北京林业大学，亚洲365，讲师

1. 植物内生放线菌次生代谢产物的发掘及其抗癌新机制研究，北京林业大学新进教师科研启动基金项目，主持；

2. 基于微流控液滴的放线菌高通量筛选培养和分离，国家自然科学基金青年基金，主持；

3.基于纸基电喷雾的多通道微流控芯片质谱联用装置的研制，国家自然科学基金专项基金项目，参与

4. 微流控液滴包覆细胞新方法研究及其在药物筛选中的应用，国家自然科学基金面上项目，参与

5. 基于化学小分子研究STAT3与心力衰竭相关靶基因RLX的相互作用及信号转导的调控规律，国家自然基金重大研究计划培育项目，参与

1. He, X.; Long, H.; Yuan, G.; Xu, X.; Zhou, Y., Investigation of Interaction of Small Natural Product Molecules and Human Telomeric G-Quadruplex and Thermal Stabilities of the Complexes by Electrospray Ionization Mass Spectrometry. Acta Physico-Chimica Sinica 2010, 26 (4), 1082-1086.
2. He, X.; Li, S.; Xu, M.; Lin, S.; Zhou, J.; Yuan, G., Investigation of non-covalent interaction of ANF promoter DNA and polyamides containing N-methylimidazole and N-methylpyrrole amino acids by electrospray ionization mass spectrometry. Rapid Communications in Mass Spectrometry 2011, 25 (7), 993-996.
3. Lin, S.; Li, S.; Chen, Z.; He, X.; Zhang, Y.; Xu, X.; Xu, M.; Yuan, G., Formation, recognition and bioactivities of a novel G-quadruplex in the STAT3 gene. Bioorganic & Medicinal Chemistry Letters 2011, 21 (19), 5987-5991.
4. Wu, X.; Luo, R.; He, X.; Yu, P.; Yuan, G., Letter: Electrospray ionization mass spectral characteristics and fragmentation mechanisms of triterpenoids in Fomes officinalis. European Journal of Mass Spectrometry 2011, 17 (3), 297-304.
5. Zhang, Z.; He, X.; Yuan, G., Regulation of the equilibrium between G-quadruplex and duplex DNA in promoter of human c-myc oncogene by a pyrene derivative. International Journal of Biological Macromolecules 2011, 49 (5), 1173-1176.
6. He, X.; Zhang, Z.; Zhang, Q.; Yuan, G., Selective recognition of G-quadruplex in the vascular endothelial growth factor gene with small-molecule natural products by electrospray ionization (ESI) mass spectrometry and circular dichroism (CD) spectrometry. Canadian Journal of Chemistry-Revue Canadienne De Chimie 2012, 90 (1), 55-59.
7. Lin, X.; Li, H.-F.; He, X.; Hashi, Y.; Lin, J.-M.; Wang, Z., Automated online pretreatment and cleanup recycle coupled with high-performance liquid chromatography-mass spectrometry for determination of deca-bromodiphenyl ether in human serum. Journal of Separation Science 2012, 35 (19), 2553-2558.
8. Zhang, Z.; He, X.; Yuan, G., Formation and recognition of G-quadruplex relevant for pilin antigenic variation in Neisseria gonorrhoeae. Canadian Journal of Chemistry-Revue Canadienne De Chimie 2012, 90 (1), 34-38.
9. He, X.; Chen, Q.; Zhang, Y.; Lin, J.-M.*, Recent advances of microchip-mass spectrometry in biological analysis. Trend in Aanlytical Chemistry.,53, 84-97, 2014.